Proteomic Analysis of Leiurus quinquestriatus quinquestriatus Scorpion Venom

The scorpion Leiurus quinquestriatus quinquestriatus, popularly known as the Palestinian yellow scorpion or as Deathstalker, has one of the most potent venoms and is of great medical importance, especially in regions of North Africa and the Middle East, but there is little knowledge about its composition. The biochemical profile of its venom is extremely valuable for understanding the envenomation, as well as for the production of the serum. 32 fractions were isolated by RP-HPLC, which were analyzed by proteomics analisys, which identified 203 peaks, of which the diversity presented with greater components of peptides acting on sodium channels (63%), potassium (25%), chlorine (1%) and calcium (1%).