Cryo-EM structure of ternary complex BCL6-CRBN-DDB1 with BCL6-760 (LDD, local refined)
收藏Protein Data Bank Japan2025-11-05 更新2026-04-19 收录
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Cryo-EM structure of ternary complex BCL6-CRBN-DDB1 with BCL6-760 (LDD, local refined) Descriptor: (3R)-3-(6-{4-[(5-chloro-4-{[3-(3-hydroxy-3-methylbutyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,3-benzimidazol-5-yl]amino}pyrimidin-2-yl)(methyl)amino]piperidin-1-yl}-1-methyl-1H-indazol-3-yl)piperidine-2,6-dione, B-cell lymphoma 6 protein, Protein cereblon, ... Authors: Zhu, J, Fang, W, Pagarigan, B. Deposit date: 2025-08-12 Release date: 2025-10-15 Last modified: 2025-11-05 Method: ELECTRON MICROSCOPY (3.15 Å) Cite: Discovery of Potent and Selective BCL6 Ligand-Directed Degrader (LDD), BCL6-760. J.Med.Chem., 68, 2025
创建时间：
2025-08-12
