A CLIC1 network coordinates matrix stiffness and the Warburg effect to promote tumor growth in pancreatic cancer. Zheng et al.
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In a study exploring the intricate relationship between PDAC matrix stiffness and the Warburg effect, Zheng et al. reveal CLIC1 as a critical mediator. Matrix stiffness increases CLIC1 levels through the Wnt/β-catenin/TCF4 pathway, correlating with adverse outcomes and tumor progression. Reducing matrix stiffness may offer therapeutic benefits by targeting CLIC1.
This data is the original immunoblotting data of the above study.
创建时间：
2024-07-27
