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KAP1/TRIM28 maintains the transcriptional state of cancer cells

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132705
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We report the genome-wide effects of KAP1 loss on the transcriptome, the chromatin state, and on recruitment of various components of the transcription machinery in the colon colorectal cancer cell line HCT116. Genome-wide binding profiles of total and phosphorylated Pol II, CDK9, and NELFE in Ctrl vs KAP1 KO cells. Nascent and steady-state RNA expression levels in Ctrl vs KAP1 KO cells. Nucleosome occupancy profiles (MNase-seq) in Ctrl vs KAP1 KO cells
创建时间:
2020-07-01
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