PLSCR1
收藏rgd.mcw.edu2025-03-25 收录
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https://rgd.mcw.edu/rgdweb/report/gene/main.html?id=1350472
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资源简介：
This gene encodes a phospholipid scramblase family member. The encoded protein is involved in disruption of the asymmetrical distribution of phospholipids between the inner and outer leaflets of the plasma membrane, resulting in externalization of phosphatidylserine. This cell membrane disruption plays an important role in the blood coagulation cascade as well as macrophage clearing of apoptotic cells. The encoded protein has additionally been implicated in gene regulation and interferon-induced antiviral responses. [provided by RefSeq, May 2022]
本基因编码磷脂酰基转移酶家族成员。所编码的蛋白质参与破坏细胞膜内外叶之间的磷脂非对称分布，导致磷脂酰丝氨酸的外化。这种细胞膜破坏在血液凝固级联反应以及巨噬细胞清除凋亡细胞过程中发挥着重要作用。此外，所编码的蛋白质还涉嫌参与基因调控和干扰素诱导的抗病毒反应。[由RefSeq提供，2022年5月]
提供机构：
Rat Genome Database
