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Shared aß T Cell Receptor Usage in Lungs of Sarcoidosis Patients with Löfgren's Syndrome [scPCR]

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NIAID Data Ecosystem2026-05-17 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP110698
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资源简介:
Expansions of CD4+ T cells utilizing TRAV12-1 and TRBV2 were found exclusively in HLA-DR3+ LS patients. These TCRs shared CDR3 homology, suggesting that these T cells are responsible for recognizing sarcoidosis-associated antigen(s) and are involved in the local alveolitis. Overall design: Analysis of TCR sequences from 13 sarcoidosis and 3 control patient blood and/or lung samples.
创建时间:
2017-10-21
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