Hypoxia down-regulates Wnt/β-catenin signaling in human OS cells.
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https://figshare.com/articles/dataset/_Hypoxia_down_regulates_Wnt_946_catenin_signaling_in_human_OS_cells_/1218536
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A, MG-63 human OS cells were cultured under hypoxia over 72 hour, and increased HIF protein expression was observed by western blot. Protein levels of active β-catenin were decreased under hypoxic conditions relative to normoxic conditions (0 hour). Actin was the loading control. B, Axin2 mRNA levels were determined as a measure of Wnt/β-catenin signaling under hypoxic conditions (72 hour, 0.5% O2) via quantitative reverse-transcription PCR (qrt-PCR) normalized to normoxia. Asterisks indicate statistical significance (*p
创建时间：
2016-02-23
