Summary of effects for variables on hippocampal volume: APOE nominal model.

n = 660; n = 2 APOE ε2 CN homozygotes excluded. Results for model which treats APOE epsilon “X” allele effects as categorical or “carrier-status” effect. APOE effect sizes of each variable are reported in terms of mm3/(unit variable). “APOEX1” denotes the effect of 1 copy of APOEX, “APOEX2” denotes the effect of 2 copies of APOEX. Unlike the results of the above model, this model does not have the assumption of dose-dependency.“:” denotes interaction terms between variables. Reference for the model is an APOE ε3/ε3 CN individual.