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Genome-wide mapping of p53-transcriptional activity in the pulmonary endothelium [ChIP-seq]. Genome-wide mapping of p53-transcriptional activity in the pulmonary endothelium [ChIP-seq]

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NIAID Data Ecosystem2026-03-11 收录
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We report a pharmacologically inducible vasculoprotective mechanism in pulmonary arterial endothelial cells (PAEC) in response to DNA damage by p53 and a novel PPARgamma/p53 transcription factor complex. Overall design: Examination of p53 and PPARγ/p53 TF complex target genes in human pulmonary arterial endothelial cells under genotoxic stress conditions.

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2019-11-01
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