CDK13 upregulation-induced formation of the positive feedback loop among circCDK13, miR-212-5p/miR-449a and E2F5 contributes to prostate carcinogenesis

To study the differential expression of genes in prostate cancer tissue and benign prostatic hyperplasia Microarray hybridization analysis of mRNA expression in two PCa samples and two benign prostatic hyperplasia tissues were performed according to the manufacturer’s protocol (Arraystar, Inc., Rockville, MD, USA).