A Landscape of Ectodomain Shedding by Quantitative Protein Terminomics
收藏NIAID Data Ecosystem2026-03-12 收录
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资源简介：
Ectodomain shedding is a proteolytic process that regulates level and function of membrane proteins. By quantitative protein terminomics consisting of N- and C-terminal peptide enrichment, TMT-labeling and mass spectrometry, we quantified protein termini in the cultured media across 10 human cell lines and identified cleavage sites on membrane proteins downregulated upon broad-spectrum metalloprotease inhibitor treatment.
创建时间：
2021-03-05
