Mechanomics RT-DC Supplementary - MEFs CAV1KO

Entry is a part of Mechanomics collection (10.6084/m9.figshare.c.5399826) that contains materials supporting findings presented in the following manuscript:
Urbanska, M., Ge, Y. et al.,
De novo identification of universal cell mechanics gene signatures
BiorXiv: https://doi.org/10.1101/2021.04.26.441418; first published: 27th April 2021, last updated: 4th Nov 2024
eLife: https://doi.org/10.7554/eLife.87930; first published: 23rd March 2023, last updated: 27th Dec 2024

This dataset contains mechanical measurement of immortalized wild type (WT) and CAV1 knock-out (CAV1KO) mouse embryonic fibroblasts derived from WT and Cav1KO littermate C57BL/9 mice (Razani, B. et al., 2001, J. Biol. Chem.).
Measurements were performed using real-time deformability cytometry (RT-DC).
_rtdc.zip - contains data acquired during the measurments in '*.rtdc' format
_tsv.zip - contains extended data in a '*.tsv' format
_glmm.zip - contains result summaries of statistical analysis comparing Young's moduli of the different cell types using generalised linear mixed effects models
Razani, B. et al. Caveolin-1 Null Mice Are Viable but Show Evidence of Hyperproliferative and Vascular Abnormalities. J. Biol. Chem. 276, 38121–38138 (2001) https://doi.org/10.1074/jbc.M105408200