The role of Tmub1 protein in the regulation of hepatic cell transcription. Rattus norvegicus

Tmub1 is involved in liver regeneration and functions as a bridging protein in tumor cell proliferation. To investigate the transcriptional profile and potential biological processes affected by Tmub1 expression in normal rat hepatocytes, microarray and bioinformatics experiments were used to identify 127 mRNAs differentially expressed between Tmub1-overexpression, Tmub1-knockdown and normal BRL-3A cells (fold change ≥ 2.5, P < 0.05). Overall design: Tmub1-overexpression, Tmub1-knockdown, 2 Negative Control and normal BRL-3A cells (fold change ≥ 2.5, P < 0.05). Five independent.