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Dearomative Indole Bisfunctionalization via a Diastereoselective Palladium-Catalyzed Arylcyanation

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https://figshare.com/articles/dataset/Dearomative_Indole_Bisfunctionalization_via_a_Diastereoselective_Palladium_Catalyzed_Arylcyanation/2126455
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The first Pd-catalyzed dearomative indole bisfunctionalization via a diastereoselective arylcyanation is reported. This method facilitates the formation of diverse indoline scaffolds bearing congested stereocenters with high levels of diastereoselectivity. This also represents the first example of a cyanation mechanism involving a 2° benzylic Pd­(II) intermediate.
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2016-02-13
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