Standard errors of the estimates of variance explained by all SNPs on the observed scale () from published analyses of case-control studies for a number of diseases vs. those predicted from the approximation theory.

Ncases: number of cases. Ncontrols: number of controls. SE(Obs.): reported standard error of the estimate of from real data analysis. SE(Approx.): standard error of calculated from our approximation theory. MDD: major depression disorder. ASD: autism spectrum disorders. ADHD: attention-deficit/hyperactivity disorder.