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Mll1 regulates the downstream gene transcription activated by TNFa. Mus musculus

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA153723
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资源简介:
Genes of mixed lineage leukemia family regulate transcription via methylating histone H3K4. we studied the role of MLL1 in innate immunity and found it selectively regulates the activation of NF-kB downstream genes mediated by TNFa. Overall design: Mll1+/+ and Mll1-/- MEF cells were treated for 4 hr with 10ng/ml TNFa or control solution respectively. The same treatment were performed three times independently and the harvested cells of same treatment were mixed together and submitted for high throughput sequencing.
创建时间:
2012-03-17
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