Gene Environment Association Studies (GENEVA). Gene Environment Association Studies (GENEVA)

The Genes, Environment and Health Initiative (GEI) is a National Institutes of Health (NIH)-wide initiative that aims to accelerate understanding of genetic and environmental contributions to health and disease. There are two components to GEI: genetics and exposure biology. The genetics component currently consists of eight programs including the Gene Environment Association Studies (GENEVA) consortium. GENEVA was initiated to: identify genetic variants related to complex diseases; identify variations in gene-trait associations related to environmental exposures; and ensure rapid sharing of data through the Database of Genotypes and Phenotypes (dbGaP). GENEVA is led by NHGRI, and consists of multiple academic institutions, including a coordinating center, two genotyping centers and 16 studies of various phenotypes, as well as several Institutes and Centers of the NIH.