Loss of p53 suppresses replication stress-induced DNA damage in ATRX-deficient neuroblastoma

To elucidate ATRX-dependent transcriptional alterations and their functional consequences, we performed a microarray analysis of Ctrl and ATRX KO NGP cells. Total RNA was extracted from Ctrl and two ATRX KO NGP clones, and a microarray analysis was performed using the Agilent-072363 SurePrint G3 Human GEv3 8 × 60 K Microarray G4851C (Agilent Technologies, Santa Clara, CA, USA).