One-Step Synthesis of Saturated Spirocyclic N‑Heterocycles with Stannyl Amine Protocol (SnAP) Reagents and Ketones
收藏NIAID Data Ecosystem2026-03-09 收录
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资源简介：
The combination of cyclic ketones and stannyl amine protocol (SnAP) reagents affords saturated, spirocyclic N-heterocycles under operationally simple reaction conditions. The resulting, N-unprotected spirocyclic amines are in great demand as scaffolds for drug discovery and development. The union of SnAP reagents and acyclic trifluoromethylketones yields α-CF3 morpholines and piperazines.
创建时间：
2016-02-16
