Transcriptomic Profiles of Immortalized Human Hepatocytes Overexpressing Intracellular Domain of NOTCH1
收藏NIAID Data Ecosystem2026-03-11 收录
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资源简介：
To investigate the effect of hyperactivation of Notch signaling in hepatocytes, an immortalized human hepatocyte cell line THLE-2 was stably transduced with control vector or plasmid harborning intracellular domain of NOTCH1 (NICD1) and the transcriptomic profiles were analyzed by RNA-seq. Immortalized human hepatocyte cell line THLE-2 cells were transduced with retrovirus vector containing empty vector or NICD1 plasmid. The mRNA profiles from NICD1-overexpressed THLE2 cell line were generated by deep sequencing using Illumina NextSeq 500. The results were compared between empty vector and NICD1-overexpressed cells.
创建时间：
2019-10-01
