首页/数据集/Structural basis of Mec1-Ddc2-RPA assembly and activation on single-stranded DNA at sites of damage. Deshpande et al

Structural basis of Mec1-Ddc2-RPA assembly and activation on single-stranded DNA at sites of damage. Deshpande et al

Mendeley Data2017-11-22 更新2026-04-09 收录

DNA损伤修复

蛋白质复合物

数据链接：

https://data.mendeley.com/datasets/83p9gjhggs/1 数据链接链接失效反馈

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This dataset contains raw microscopy images of 4NQO-treated cells from Figure 3E of the manuscript.

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创建时间：

2017-11-22

结构生物学

蛋白质复合物

PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P03H10 from the F2X-Universal Library Descriptor: (3S)-3-amino-4-(2-fluorophenyl)butanoic acid, A1 cistron-splicing factor AAR2

Protein Data Bank Japan2024-05-22 更新100

Discovery of Isaindigotone Derivatives as Novel Bloom’s Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair

DNA损伤修复

抗癌药物设计

Homologous recombination repair (HRR), a crucial approach in DNA damage repair, is an attractive target in cancer therapy and drug design. The Bloom syndrome protein (BLM) is a 3′–5′ DNA helicase that

NIAID Data Ecosystem40

Complex III assembly

生物信息学

蛋白质复合物

This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which al

reactome.org40

Effect of DNA break-induced transcriptional repression on genome stability. Homo sapiens

DNA损伤修复

染色质调控

Cohesin and the PBAF chromatin remodelling complex are required to repress transcription at sites of DNA double strand breaks. To investigate this and rule out known sister-chromatid dependent functio

NIAID Data Ecosystem60

Data and code for analyzing DSB mobility

DNA损伤修复

肌动蛋白动力学

Double-strand breaks (DSBs) are critical lesions in genomic DNA, and their accurate repair is essential for maintaining genome stability. The nuclear actin cytoskeleton has been implicated in homology

DataCite Commons2025-10-22 更新40

Structural basis of Mec1-Ddc2-RPA assembly and activation on single-stranded DNA at sites of damage. Deshpande et al

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