Distribution of mutation signatures.
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When subdividing GNAQ/11 mutation signatures, A>C mutations were predominantly found in in the choroid as opposed to A>T mutations which were not location dependent. The presence of lipofuscin in A>C signature tumors supports the hypothesis that A>C mutations are likely to be caused by solar light damage, however this did not reach statistical significance.Distribution of mutation signatures.
创建时间：
2015-12-03
