NSUN2 regulates thyroid cancer-associated alternative splicing switches
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP464900
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资源简介：
In this research, we find that both m5C deposition in splice site boundaries and in splicing, direct AS switches of specific thyroid cancer- associated transcripts. We also show that several of the AS events validated in vitro are associated with a poor overall survival rate for patients with thyroid cancer, suggesting the use of these AS events as a novel potential prognostic biomarker. Overall design: We knockout NSUN2 in Cal-62 cells and performed the RNA-seq analysis in order to exam the transcriptome after NSUN2 KO.
创建时间：
2025-03-20
