Brain-specific SIRT6-KO mice present increased DNA damage, learning impairments, and neurodegenerative phenotypes, placing SIRT6 as a key protein in preventing neurodegeneration. In the aging brain, S
We established the transcriptional profile of brain aging and examine the global effects of vitamin E supplementation on age-related alterations in expression in the aged mouse brain. Keywords: expres
Aging is a major risk factor for late-onset Alzheimer’s disease (LOAD). How aging contributes to the development of LOAD remains elusive. In this study, we examined multiple large-scale transcriptomic
Comparison of gene expression and ribosome profiles from Nothobranchius furzeri brain of 2 age groups. The RNA-seq and ART-seq data comprise 2 groups: 6 and 26 weeks. Jena Centre for Systems Biology o