Body weight, plasma lipids and inflammation markers over time.

Lipids and inflammation markers determined in EDTA plasma obtained by tail bleeding after 5 h of fasting. Values of the time points t = 0, 6 and 12 weeks are shown. Letters in brackets indicate the main origin of the inflammation markers: liver (L), adipose tissue (A) or vasculature (V). Values are means ± SEM. Significance of post-hoc analysis is indicated * P<0.05, **P<0.01, ***P<0.001 (as compared to the starting level at t = 0).