Ten-eleven translocation (TET) proteins play key roles in regulating the methylation status of DNA through oxidizing methylcytosines (5mC), generating 5-hydroxymethylcytosines (5hmC) that can both ser

NIAID Data Ecosystem60

DataSheet_1_Identification of Differentially Expressed Human Endogenous Retrovirus Families in Human Leukemia and Lymphoma Cell Lines and Stem Cells.zip

内源性逆转录病毒

癌细胞研究

Endogenous retroviruses (ERVs) are becoming more and more relevant in cancer research and might be potential targets. The oncogenic potential of human ERVs (HERVs) has been recognized and includes imm

NIAID Data Ecosystem30

ERV-L Elements: a Family of Endogenous Retrovirus-Like Elements Active throughout the Evolution of Mammals

内源性逆转录病毒

哺乳动物分子系统发育

We have previously identified in the human genome a family of 200 endogenous retrovirus-like elements, the HERV-L elements, disclosing similarities with the foamy retroviruses and which might be the e

PubMed Central60

Active endogenous retroviral elements in human pluripotent stem cells are functional in regulating host gene expression

内源性逆转录病毒

基因表达调控

Human endogenous retroviruses were also called LTR elements which can be bound by transcription factors and marked by different histone modifications. In previous studies, LTR had been considered harm

NIAID Data Ecosystem50

Trim33 binds and silences a class of young endogenous retroviruses in the mouse testis

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