Mutations spectra in the indicated strains.

a the following nomenclature is used: “t” and “ori” refer to the telomere and the replication origin 3006/7, respectively; “<“ and ”>” indicate the RTS1-RFB and its polarity (< blocks replication forks moving from the ori3006/7 towards the telomere, and > blocks replication forks moving from the telomere towards the origin 3006/7).
b number of events.
c event/cell/division ×10−8 ± standard error. The % of each mutation events was used to balance the rate of mutation.
d value not significantly different from those for the t-ura4-ori strain (spontaneous events).