T cells specific for alpha-myosin drive immunotherapy related myocarditis

Alliance of Genome Resources2026-08-01 收录

免疫治疗相关心肌炎

单细胞TCR测序

数据链接：

http://www.informatics.jax.org/gxd/htexp_index/summary?arrayExpressID=GSE213486 数据链接链接失效反馈

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Single cell RNA and TCR sequencing of murine hearts and human alpha-myosin expanded blood Single cell RNA and TCR sequencing

single-cell RNA and TCR sequencing of TRM CD8+ T cells sorted from 8 HGSOC tumors

肿瘤免疫微环境

单细胞TCR测序

Purpose: Characterization of the gene expression profile and TCR profile of CD8+ TILs (TRM and re-circulating) from HGSOC to understand the immunogenicity of ovarian cancer Overall design: We FACs-sor

NIAID Data Ecosystem40

Additional file 3: Table S3. of Single-cell TCRseq: paired recovery of entire T-cell alpha and beta chain transcripts in T-cell receptors from single-cell RNAseq

单细胞TCR测序

免疫组库分析

Results of scTCRseq and VIDJIL run on simulated scRNAseq data at different read lengths and coverage. Provided as a separate Excel file. (XLSX 10 kb)

Figshare2016-12-16 更新10

The T cell receptor landscape of pediatric brain tumors

肿瘤免疫微环境

单细胞TCR测序

Unprocessed single-cell RNA-seq reads from four DIPG, three ependymoma (EPN), and two low-grade glioma (LGG) samples were combined into a single RDS file. Similarly, the corresponding alpha/beta TCR-s

Zenodo2025-02-10 更新10

Tumor-associated Tregs obstruct anti-tumor immunity by promoting T cell dysfunction and restricting clonal diversity in tumor-infiltrating CD8+ T cells. Tumor-associated Tregs obstruct anti-tumor immunity by promoting T cell dysfunction and restricting clonal diversity in tumor-infiltrating CD8+ T cells

肿瘤免疫微环境

单细胞TCR测序

We investigated how accumulation of Tregs contributes to T cell dysfunction and clonal constriction of tumor-infiltrating CD8+ T cells. Resected melanoma atissues from tumor-bearing mice were analyzed

NIAID Data Ecosystem20

T cells specific for alpha-myosin drive immunotherapy related myocarditis. T cells specific for alpha-myosin drive immunotherapy related myocarditis

免疫治疗相关心肌炎

单细胞TCR测序

Single cell RNA and TCR sequencing of murine hearts and human alpha-myosin expanded blood Overall design: Single cell RNA and TCR sequencing

NIAID Data Ecosystem10