Cohesin is a key determinant of interphase chromosome domain architecture
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Cohesin is a key determinant of interphase chromosome domain architecture
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2013-12-11
相关数据集
Cohesion is established during DNA replication utilising chromosome associated cohesin rings as well as those loaded de novo onto nascent DNAs
Cohesin is established by two parallel pathways during DNA replication. Chromosome associated cohesin is converted to cohesive structures and this depends on four protein associated with the replisome
NIAID Data Ecosystem50
Sensitivity of cohesin-chromatin association to high salt treatment corroborates non-topological mode of loop extrusion
Cohesin is a key organizer of chromatin folding in eukaryotic cells. Two basic activities of this ring-shaped protein complex are maintenance of sister chromatid cohesion and establishment of long-ran
NIAID Data Ecosystem20
Cohesin removal reprograms mitotic gene expression upon mitotic entry [RNA-seq I]. Cohesin removal reprograms mitotic gene expression upon mitotic entry [RNA-seq I]
During mitosis, the genome is restructured to facilitate chromosome segregation, accompanied by dramatic changes in gene expression. However, the mechanisms that underlie mitotic transcriptional regul
NIAID Data Ecosystem20
The cohesin release factor WAPL restricts chromatin loop extension.. The cohesin release factor WAPL restricts chromatin loop extension.
This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
NIAID Data Ecosystem30
PDS5A and PDS5B differentially affect gene expression without altering cohesin localization across the genome [RNA-seq]. PDS5A and PDS5B differentially affect gene expression without altering cohesin localization across the genome [RNA-seq]
Purpose: Cohesin is an important structural regulator of the genome. Whether cohesin HEAT repeat accessory proteins PDS5A and PDS5B differentially contribute to cohesin function remains unclear. The p
NIAID Data Ecosystem20
