Characterization of influenza A virus variants with reduced susceptibility to baloxavir isolated from patients in Japan, Aug 02 '19

Here we report the isolation of influenza A/H1N1 2009 pandemic (A/H1N1pdm) and A/H3N2 viruses carrying an I38T mutation in the polymerase acidic (PA) protein, which confers reduced susceptibility to baloxavir, from patients before drug treatment and from patients after treatment with this drug in Japan.