In-vitro efficacy of fluoroquinolones and carbapenems against biofilm-forming and non-forming non-fermenting gram-negative bacteria isolated from clinical specimens

Non-fermenting gram-negative bacteria (NFGNB) pose a public health threat due to their tendency to cause multidrug-resistant and/or biofilm-associated infections. This cross-sectional study analyzed antibiograms, biofilm formation, and minimum inhibitory concentrations (MICs) of quinolones and carbapenems in NF-GNB from clinical specimens in a tertiary care hospital. Clinical specimens were processed for bacterial isolation and identification. Quinolone- and carbapenem-resistant Acinetobacter calcoaceticus-baumannii (ACB) complex and Pseudomonas aeruginosa, confirmed by disc diffusion, were tested for MICs of quinolones and carbapenems using broth microdilution. Biofilm formation was assessed by the microtiter plate method. Statistical analyses were performed in SPSS 17.0. A total of 92 NFGNB were isolated from patients (median age: 24 years, 56.52% female), primarily with urinary tract infections (40.23%). Biofilm formation was detected in 23.94% (17/71) of the ACB ..., Patients' demographics and laboratory results, including microbiological analyses, were collected through patient information sheets. The sheet detailed for demographic information, such as age group and gender of the infected patients; clinical information, including clinical samples; microbiological findings comprising bacterial genera, antimicrobial resistance patterns, biofilm formers or non-formers, inhibitory concentrations of fluoroquinolones (norfloxacin, ciprofloxacin, ofloxacin, and levofloxacin) and carbapenems (imipenem and meropenem). Considering that the Patient identification number and Specimen number were human subject data and must be anonymized, these identifiers were removed from the dataset. Exact or direct age is removed and is categorized as an age group in order to anonymize the data. Any missing or unclear records were clarified by communicating with healthcare providers, patients, or families (using the phone numbers from the patient information sheet). The stu..., # In-vitro efficacy of fluoroquinolones and carbapenems against biofilm-forming and non-forming non-fermenting gram-negative bacteria isolated from clinical specimens

Dataset DOI: [10.5061/dryad.ghx3ffc1f](10.5061/dryad.ghx3ffc1f)

## Description of the data and file structure

Comparative In-Vitro Efficacy of Fluoroquinolones and Carbapenems among Biofilm-Forming and Non-Forming Non-Fermenters Isolated from Clinical Specimens

The dataset is of hospital-visiting individuals with infection due to non-fermenter bacteria, i.e., *Acinetobacter calcoaceticus-baumanii* complex and *Pseudomonas aeruginosa*.

The dataset comprises of single sheet. The sheet details for demographic information, such as age group and gender of the infected patients; clinical information, including clinical samples; microbiological findings comprising bacterial genera, antimicrobial resistance patterns, biofilm formers or non-formers, inhibitory concentrations of fluoroquinolones (norfloxacin, ciprofloxacin, ofl..., We received consent from the study participants to publish the de-identified data in the public domain.

Considering that Patient identification number (e.g., P1, P18, P128, etc.) and Specimen number (S5, S17, S6, etc.) were human subject data and must be anonymized, these identifiers were removed from the dataset. Exact or direct age is removed and is categorized as an age group in order to anonymize the data.