Crystal Structure of CDK2 in complex with compound 22
收藏Protein Data Bank Japan2024-03-06 更新2026-03-21 收录
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Crystal Structure of CDK2 in complex with compound 22 Descriptor: 1-[(1~{S})-1-(4-chloranyl-3-fluoranyl-phenyl)-2-oxidanyl-ethyl]-4-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one, Cyclin-dependent kinase 2 Authors: Yin, J, Wang, W. Deposit date: 2016-05-20 Release date: 2016-07-06 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development. J.Med.Chem., 59, 2016
创建时间：
2016-05-20
