five

Effect of G0s2 and Rgs16 knockdown on hepatic transcriptome

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE181262
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We identified 2 leading gene candidates (G0s2 and Rgs16) in response to circadian, diet and genetic manipulations by a large-scale transcriptome analysis. To examine the impact of G0s2 and Rgs16 on liver functions, we carried out adenovirus-mediated liver-specific knockdown of both genes and performed RNA-seq analysis. Comparison between liver samples of shLacZ control and G0s2 or Rgs16 knockdown (shG0s2 or Rgs16) mice.
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2021-08-03
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