Transcriptomic computational analysis of mastic oil-treated Lewis lung carcinomas. Mus musculus

Mastic oil from Pistacia lentiscus variation chia, a blend of bioactive terpenes with recognized medicinal properties, has been recently shown to exert anti-tumor activity. Lewis lung carcinoma (LLC) cells are mastic oil-susceptible cells and were used in this work to study the effects of mastic oil at the transcriptomic level. Overall design: Expression profiling by array. LLC cells were treated with mastic oil or DMSO (control) for 3h, 6h, 12h, 24h, or 48h. Two replicates per treatment/time point. Data were normalized using rank invariant and quantile normalization.