Compilation of APOBEC3G-induced mutations (sorted by type) and APOBEC3G motif preference.

Complex mutations are defined as two or more single base changes, where the 5′- and 3′-most changes are within ten nucleotides of one another. The 3′ C (underlined) in each motif triplet undergoes deamination. In rare cases, deamination occurred at an internal C within a run of >3 C's. Two complex mutations in UNG1 were omitted from computation of motif preference. PUNG1 and ung1Δ when comparing proportions of mutation types. P>0.05 when comparing proportions of motifs.