Single-cell transcriptomics of adult gd T-cell lineage commitment highlights its TCR-instructive nature II

Single cell RNA-seq study of T lymphocyte differentiation WT and LAT deficient mice in order to deciphy gd T-cell lineage commitment. Overall design: Single cell RNA-seq study of T lymphocyte differentiation. Two datasets were produced, corresponding to either double negative cells (DN, i.e. CD8– and CD4–) or total thymocytes (TOT) that were both sorted for live cells.