Fibroblast-like synoviocytes derived from patients with rheumatoid arthritis

ChEBI2006-01-18 更新2026-07-21 收录

类风湿关节炎

滑膜细胞研究

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-4061 数据链接链接失效反馈

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Fibroblast-like synoviocytes derived from patients with rheumatoid arthritis

创建时间：

2006-01-18

基于机器学习和网络药理学分析类风湿关节炎中大麻二酚治疗双靶点机制

类风湿关节炎

机器学习

根据全球疾病负担研究（GBD 2021），类风湿关节炎（RA）在全球约有1790万人受影响，2021年造成约37,300人死亡。目前RA的临床治疗主要涉及非甾体抗炎药和生物制剂。然而，这些疗法存在相当大的局限性。一方面，疗效存在显著个体差异，同时部分患者未能实现临床缓解。另一方面，长期服用容易引发严重不良反应，如胃肠道损伤和感染。为解决这些限制，植物提取物因其天然来源、良好的生物相容性和多靶点特异

DataCite Commons2025-11-25 更新130

Risk factors for developing TB adjusted by age at entry, sex, the use of corticosteroids, comorbidities and Charlson comorbidity index (CCI) in rheumatoid arthritis cohort.

类风湿关节炎

结核病风险

Risk factors for developing TB adjusted by age at entry, sex, the use of corticosteroids, comorbidities and Charlson comorbidity index (CCI) in rheumatoid arthritis cohort.

NIAID Data Ecosystem40

Comparison of carotid intima-media thickness (cIMT) according to CD40 rs1883832, rs4810485 and rs1535045 alleles in an adjusted ANCOVA model.

遗传关联研究

类风湿关节炎

*Analyses adjusted for sex, age at rheumatoid arthritis diagnosis, follow-up time, and traditional cardiovascular risk factors. **Conditional analysis of the rs1883832 and rs1535045 CD40 gene variants

NIAID Data Ecosystem20

Data_Sheet_1_C-Reactive Protein Promotes the Activation of Fibroblast-Like Synoviocytes From Patients With Rheumatoid Arthritis.PDF

类风湿关节炎

CRP (C反应蛋白)

Objective: To evaluate the biological effect and mechanisms of C-reactive protein (CRP) on the activation of fibroblast-like synoviocytes (FLSs) from patients with rheumatoid arthritis (RA). Study des

NIAID Data Ecosystem50

Demographics of SLE and RA patients and healthy donors.

系统性红斑狼疮

类风湿关节炎

Except where otherwise indicated, the values expressed are means ± standard errors of the means (ranges). There were no significant differences between the patients with SLE, the patients with RA, and

NIAID Data Ecosystem20

Fibroblast-like synoviocytes derived from patients with rheumatoid arthritis

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