Dissecting cell-type-specific roles of androgen receptor in prostate homeostasis and regeneration through lineage tracing
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=86d6e6efd7b5b82f1909e999d02721e6
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资源简介：
We used RNA-seq to compare the gene expression profiles of adult mouse prostate luminal cells and luminal cells that have the androgen receptor (AR) gene deleted. Our analyses show that AR-null luminal cells have altered expression levels of genes involved in cell-matrix adhesion, cytoskeleton regulation, and MAPK and TGF-beta signaling pathways. These results are consistent with our finding that AR-null luminal cells have abnormal cell morphology and loss of cell polarity.
提供机构：
University of California Santa Cruz
创建时间：
2022-02-20
