Coordinated genomic control of ciliogenesis and cell movement by Rfx2
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https://www.ncbi.nlm.nih.gov/sra/SRP029582
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资源简介:
We have performed a systems-level analysis of the RFX/Daf-19 family transcription factor, Rfx2. Using a combination of high-throughput sequencing of Rfx2-regulated transcripts and chromosomal binding sites, we provide a comprehensive accounting of the target genes by which Rfx2 controls ciliogenesis and cilia beating in vertebrates. Overall design: RNA-seq: two biological replicates for control and RFX2 knockdown by morpholino injection, ChIP-seq: RFX2-GFP pulldown with GFP antibody, GFP only expression used as control
创建时间:
2019-09-23



