Transcriptomic response to Klotho deficiency in the renal distal convolution
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https://www.ncbi.nlm.nih.gov/sra/SRP470132
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To assess the transcriptomic response to Klotho deficiency in the renal distal convolution (DC), we isolated DC cells from control and DC-specific Klotho KO mice using COPAS (Complex Object Parametric Analyzer and Sorter). Further comprehensive and unbiased RNA-seq identified altered transcripts associated with canonical MAPK pathway, as well as many novel targets of Klotho. Overall design: We included 4 male mice in each control and KO group. The DC cells were isolated using COPAS. The transcriptomic repsonse was assesed by RNA-seq
创建时间:
2023-12-15



