Genomic integrity safeguards pluripotency in embryonic stem cells
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE111982
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资源简介：
Illumina BeadChip array analyses of mouse embryonic stem cell gene expression profiles in the presence of or upon knockdown of 4 candidate factors regulating genomic integrity -- Chek1, Ppm1g, Ppp2r1b and Bub1b. An ES complementation 'rescue' system was employed to measure the effects of knockdown (minus Dox). The 4 candidate factors are rescued to wildtype levels in the presence of Dox (plus Dox). A control rescue ES cell line, with a Luciferase-targeting shRNA, was also assessed. Total of 30 samples; Chek1_R (+/-Dox), Ppm1g_R (+/-Dox), Ppp2r1b_R (+/-Dox), Bub1b_R (+/-Dox), Control_R (+/-Dox); all performed in triplicates.
创建时间：
2019-09-03
