Inhibitors of Jak2 Kinase domain
收藏Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Inhibitors of Jak2 Kinase domain Descriptor: 5-CHLORO-N2-[(1S)-1-(5-FLUOROPYRIMIDIN-2-YL)ETHYL]-N4-(5-METHYL-1H-PYRAZOL-3-YL)PYRIMIDINE-2,4-DIAMINE, TYROSINE-PROTEIN KINASE JAK2 Authors: Read, J, Green, I, Pollard, H, Howard, T, Mott, R. Deposit date: 2010-03-26 Release date: 2010-12-15 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Discovery of 5-Chloro-N2-[(1S)-1-(5-Fluoropyrimidin-2-Yl) Ethyl]-N4-(5-Methyl-1H-Pyrazol-3-Yl)Pyrimidine-2,4-Diamine (Azd1480) as a Novel Inhibitor of the Jak/Stat Pathway J.Med.Chem., 54, 2011
创建时间:
2010-03-26



