Quercetin Prevents Intestinal Stem Cell Aging via Scavenging ROS and Inhibiting Insulin Signaling in Drosophila. Quercetin Prevents Intestinal Stem Cell Aging via Scavenging ROS and Inhibiting Insulin Signaling in Drosophila

Adult stem cells undergo functional degeneration during aging. Quercetin exhibits many beneficial effects against aging and aging-related diseases. Using Drosophila as a model, we explore the efficacy of quercetin against adult stem cell aging and provide effective and feasible therapeutic solutions for preventing the aging-related functional decline of stem cells. Overall design: Comparative gene expression profiling analysis of RNA-seq data for Drosophila intestine with and without quercetin supplementation