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Protoanemonin: A new natural quorum sensing inhibitor that selectively activates iron starvation response

ChEBI2012-06-12 更新2026-07-21 收录

群体感应抑制

天然产物抗微生物活性

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-27674 数据链接链接失效反馈

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资源简介：

Protoanemonin: A new natural quorum sensing inhibitor that selectively activates iron starvation response

应用场景：

创建时间：

2012-06-12

水产病原菌防控

群体感应抑制

Vibrio campbellii is one of the major bacterial pathogens for animals reared in aquaculture, affecting both vertebrates and invertebrates, and causes significant economic losses. It is now evident tha

NIAID Data Ecosystem140

异甘草素作为群体感应抑制剂可减弱铜绿假单胞菌的毒力和致病性。

群体感应抑制

抗菌药物开发

这项研究表明，查尔酮化合物异甘草素（ILG）表现出有效的 QS 活性。ILG 下调 QS相关基因 lasR、lasI、rhlR、rhlI、pqsA、pqsR、lasA、rhlA 和 phzA1 的表达，并抑制亚抑制浓度的蛋白酶、弹性蛋白酶、脓脓素和鼠李糖脂等毒力因子的产生。此外，ILG 减弱了与感染和抗生素耐药性相协调的生物膜形成和运动。大白菜、黑腹果蝇和秀丽隐杆线虫感染模型揭示了 ILG 的

DataCite Commons2025-02-26 更新60

Chryseobacterium sp. CH21 Genome sequencing and assembly. Chryseobacterium sp. CH21

耐药组分析

群体感应抑制

Resistome and quorum sensing inhibition potential of fish-associated Chryseobacterium spp.

NIAID Data Ecosystem50

Prenylated Diresorcinols Inhibit Bacterial Quorum Sensing

群体感应抑制

抗毒力治疗

Current treatment options for bacterial infections are dependent on antibiotics that inhibit microbial growth and viability. These approaches result in the evolution of drug-resistant strains of bacte

NIAID Data Ecosystem70

Table_1_Bioactive Properties of Syzygium cumini (L.) Skeels Pulp and Seed Phenolic Extracts.xlsx

植物提取物抗菌活性

群体感应抑制

The emergence of bacterial strains resistant to different antibiotics has prompted the search for new sources of antimicrobial compounds. Studies have shown that jambolan [Syzygium cumini (L.) Skeels]

NIAID Data Ecosystem60

Protoanemonin: A new natural quorum sensing inhibitor that selectively activates iron starvation response

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