Expression data from mouse pontine nucleus. Expression data from mouse pontine nucleus

During brain development, layer 5 neurons distributed across most areas of the neocortex innervate the pontine nuclei (basilar pons) by the initiation and extension of collateral branches interstitially along their corticospinally extending axons. We used microarrays to compare gene expression profiles of pontine nucleus when axon collaterals towards the pontine nucleus start to extend (embryonic day 17.5 (E17.5) to postnatal day 1 (P1)), and/or throughout the development (E17.5-P14) in order to understand genetic programs that regulate axon collaterals formation. Overall design: Pontine nucleus was dissected out from each developmental stage of the mouse brain and subjected to total RNA preparation and hybridization on Affymetrix microarrays.