vTK/GCV induced liver failure in FVB/N mice.
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GCV was administered to vTK+ and vTK-FVB/N mice for 5 days. Health status ranged from excellent (+++), to poor (++), to critical. ALT and AST levels were determined for blood draws obtained at 1 hour prior to (T0) and at the end of (Tf) the dosing period. Livers ranged from healthy/normal (red), to very pale at the end of the study.
创建时间:
2015-12-02



