Proteomic changes in the colon of mice with epithelial specific deletion of Apc or Apc/Dhps

C57BL/6 mice with a tamoxifen (TAM)-inducible disruption of Apc (CDX2P-CreERT2;Apc fl/fl) or Apc and Dhps (CDX2P-CreERT2;Apc fl/fl;Dhps fl/fl) were injected or not with one intraperitoneal injection 4.5 mg/kg TAM. After 35 days, the following colon biopsies were harvested: normal tissues from mice that did not receive TAM, non-tumor tissues from mice treated with TAM, and tumors from mice treated with TAM. Biopsies from 5 mice were collected for the following sample groups: (1) Apc Control; (2) Apc/Dhps Control; (3) Apc+TAM non-tumor; (4) Apc/Dhps+TAM non-tumor; (5) Apc+TAM tumor; (6) Apc/Dhps+TAM tumor