Human prolyl endopeptidase (PREP) - complex with KYP2047
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Human prolyl endopeptidase (PREP) - complex with KYP2047 Descriptor: (2S)-1-[1-(4-phenylbutanoyl)-L-prolyl]pyrrolidine-2-carbonitrile, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... Authors: Fucci, I.J, Thakur, K, Yoo, E, Monteiro, D.C.F. Deposit date: 2025-08-28 Release date: 2026-01-21 Last modified: 2026-01-28 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Structure-Guided Optimization of 4-Chloro-Pyrazolopyridine Analogs for Covalent PREP Inhibition. J.Med.Chem., 69, 2026
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2025-08-28
