Organophotocatalytic functionalization of 3,4-dihydroquinoxalin-2-ones with isoxazol-5-amines using visible light

An organophotocatalytic strategy for the functionalization of 3,4-dihydroquinoxalin-2-ones with isoxazol-5-amines is reported. Using commercially available organophotocatalysts under visible light irradiation and mild reaction conditions, a series of 22 derivatives have been synthesized. This process was also scaled up to 1 mmol, revealing the formation of an isoxazol-2-one derivative as byproduct. The mechanism of this transformation has also been investigated through steady-state luminescence quenching experiments, among other techniques.

The dataset contains 1H NMR, 13C NMR and DEPT spectra for the new compounds prepared in the associated manuscript.