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Loss of Cdx2 drives direct trophoblast differentiation into trophoblast giant cells via TFAP2C (ATAC-Seq)

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE181053
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资源简介:
In this experiment, the effect of reduced CDX2 expression on chromatin accessibility in trophoblast stem cells (TSCs) was assayed using ATAC-seq. High read depth transposase accessible chromatin profiles were generated using 50,000 cells. shRNA vectors containing a constitutively active mCherry cassette to visualise and isolate transfected and non-transfected populations. Positively transfected CDX2 knockdown TSCs were compared with control transfected and untransfected TSC populations.
创建时间:
2022-07-01
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